Joshua Goldman
Joshua Goldman
min read · August 14, 2025 · Entertainment

Teddi Mellencamp's Heartfelt Plea: Battling Stage 4 Cancer and Anxiety from Immunotherapy

Teddi Mellencamp turned to her fans for advice Thursday as she opened up about struggling with immunotherapy amid her stage four cancer battle

Teddi Mellencamp Spills Tea on Marriage, Infidelity, and Cancer Battle

In a shocking turn of events, former Real Housewives of Beverly Hills star Teddi Mellencamp has opened up about her tumultuous marriage, infidelity, and ongoing cancer battle in an emotional Instagram video. The 44-year-old reality TV personality, who recently revealed she is battling stage four cancer, took to social media to seek advice from her fans regarding the intense anxiety caused by immunotherapy treatment.

With a shaved head on full display, Teddi candidly shared her struggles with the excruciating effects of immunotherapy, which harnesses the body's immune system to fight the disease. "For all of you who have gone through immunotherapy, did you guys experience severe anxiety?" she asked her followers. "I'm sitting here right now feeling overwhelmed with anxiety for no apparent reason. Is this common? What have you done to help alleviate your symptoms?"

The former Real Housewives of Beverly Hills star, 44, shared an emotional video on Instagram, showing herself in bed with her shaven head on full display as she detailed the intense effects of the cancer treatment that harnesses the body¿s immune system to fight the disease

Teddi's emotional plea comes after a recent appearance on The Jamie Kern Lima Show, where she revealed the heart-wrenching details of her marriage woes and infidelity. The mother-of-three, who shares Slate, 12, Cruz, 10, and Dove, 5, with estranged husband Edwin Arroyave, confessed that discovering his affair with a mutual friend just days before her 2017 debut on RHOBH left her "broken." Teddi explained how she begged him to stay after the betrayal, saying it was "the first time in my life where I was like, 'How will I show up every day with a smile on my face and raise these kids, and be this perfect wife?'"

Teddi's confession also touched on her experiences on Housewives, where she admitted to "faking" her way through filming to protect her family. "People say, 'Oh you seem kind of quiet or you were kind of passive'—but that's not really who you are," she revealed. "I was coping. I was so scared that someone was going to find out and ruin my family's life."

The reality star, who filed for divorce from her husband of 13 years on November 1, 2024, citing irreconcilable differences, has maintained a close and amicable co-parenting relationship with Edwin despite their marriage woes. When asked about the alleged affair with horse trainer Simon Schroeder, which made headlines in late 2024, Teddi diplomatically replied, "I've never talked about it at all, just because of the kids, and I've never wanted anybody to have a guarantee whether it happened or didn't happen."

The message comes after Mellencamp revealed she discovered now-estranged husband Edwin Arroyave¿s affair with a mutual friend just days before her 2017 debut on The Real Housewives of Beverly Hills; (pictured with Edwin in 2019)

However, her voice cracked as she confessed that she did engage in behaviors that hurt others. "To this day, does it still hurt my heart and I wonder if that's why I got cancer? Yes, like it was my payback," she tearfully revealed.

Teddi's emotional journey has been marred by controversy, with her divorce proceedings put on hold due to her ongoing battle with stage four cancer. Fans have taken to social media to offer words of encouragement and support for the reality star, who is currently undergoing immunotherapy treatment.

As Teddi navigates this challenging time in her life, she's seeking advice from those who have been through similar experiences. Will you be offering any words of wisdom or solidarity? Share your thoughts and well-wishes with Teddi on The Scholarly Note.

The mother-of-three, who shares Slate, 12, Cruz, 10, and Dove, 5, with Edwin, explained how the betrayal affected her first season on Housewives, forcing her to ¿fake¿ her way through filming to protect her kids; (pictured on the show)

Readers' Comments

  • "Teddi, I'm so sorry to hear about your struggles with immunotherapy and cancer. You're an inspiration for seeking help and being open about your journey" - @SARAH123
  • "I completely understand what you mean about the anxiety caused by immunotherapy. I went through a similar experience and it was overwhelming at times, but I found that deep breathing exercises really helped me cope" - @JENNY90
  • "Teddi, I'm so glad you're being open about your struggles with infidelity. It takes courage to admit when we've made mistakes, and I admire your willingness to do so" - @KIMBERLY2024

Share Your Thoughts

Have you gone through immunotherapy treatment? How did you cope with the anxiety caused by it? Share your experiences in the comments below.

What are your thoughts on Teddi's confession about her marriage woes and infidelity? Do you think she's being honest or is there more to the story?

As Teddi continues to navigate this challenging time, what advice would you give her regarding her cancer battle and co-parenting relationship with Edwin?