Joshua Goldman
Joshua Goldman
min read · July 17, 2025 · Entertainment

Christina Applegate Unveils Her Struggles: Memoir Amid MS Battle

Christina Applegate, 53, has announced that she is set to release a new memoir titled You With The Sad Eyes amid her ongoing multiple sclerosis (MS) battle; seen in 2023 in L.A.

SCANDALOUS! Christina Applegate Spills All in Jaw-Dropping Memoir, Opens Up About MS Battle and Tumultuous Childhood!

The world is about to get a major dose of unfiltered reality from none other than Dead To Me star Christina Applegate, as she prepares to release her highly anticipated memoir, You With The Sad Eyes. And trust us, it's going to be a wild ride!

According to insiders close to the project, the 53-year-old actress has been working on the book for months, pouring her heart and soul into a deeply personal and unflinchingly honest account of her life - including her struggles with multiple sclerosis (MS) and her tumultuous childhood.

The Dead To Me star expressed that she made the decision to pen the book when she was 'forced to slow down'; seen in 2024 in L.A.

As The Scholarly Note reports, Applegate's memoir is set to hit shelves in March 2026, courtesy of Little, Brown And Company. But don't expect just another celebrity tell-all; this book promises to be a game-changer!

"I've had a career in TV and film since I was 3 years old, and I loved it," Applegate revealed in a statement. "But with MS, all the things I thought were important shifted." She confessed that writing the memoir was a cathartic experience, allowing her to finally find meaning in the midst of chaos.

And what can readers expect from this explosive tell-all? For starters, get ready for some serious TMI! Applegate opens up about her childhood, revealing the dark secrets and insecurities she's kept hidden for years. She also shares her experiences with past abuse and assault - a topic that's sure to spark outrage and sympathy in equal measure.

Applegate continued, 'But it will be real. It will be filled with the ups and downs, the humor and grief of life. So here I am. Real me. Lots to say'; seen in 1989 in L.A.

But don't worry, folks; this isn't just a sob story. Applegate is quick to emphasize that her book won't be some big violin-scratching-for-her-life sob fest. Instead, it'll be a real, no-holds-barred account of the ups and downs she's faced - with plenty of humor and heart.

As Bryn Clark, executive editor at Little, Brown and Company, put it: "Christina speaks to the power of embracing the messiness and temporality of life instead of hiding behind the plastic veneer of our modern world. We have no time to waste on falsehoods and perfection."

So, what's the takeaway from this mouthwatering memoir? According to Applegate herself, it's that even in the darkest moments, there's always hope - and a whole lot of humor! As she puts it: "The pain will be matched by the joy, the losses mitigated by the extraordinary, the weight of life lifted by my signature comedic genius..."

From 1987 through 1997, the actress portrayed the character of Kelly Bundy in the sitcom Married... With Children (seen above far left)

In other words, get ready for some serious LOLs from this feisty actress-turned-author!

Now, we know what you're thinking: How did Applegate come to write such a brave and vulnerable memoir? The answer lies in her own journey with MS. As she revealed on her MeSsy podcast last year, writing the book was a way for her to process her experiences and find solace in the midst of her health battle.

So, what can we expect from this unforgettable memoir? For starters, get ready for some serious drama! Applegate dishes about her time on Married... With Children, where she played Kelly Bundy from 1987-1997. She also opens up about her experience with MS, sharing the painful moments the public didn't see.

From 2019 through 2022, she played Jen Harding in the critically-acclaimed series Dead To Me alongside Linda Cardellini and James Marsden

And don't even get us started on the Anchorman franchise - or her critically-acclaimed series Dead To Me! Applegate talks candidly about her time on set, revealing the inner workings and behind-the-scenes secrets that'll leave you hooked!

So, are you ready to get up close and personal with Christina Applegate? Then get ready for a wild ride with You With The Sad Eyes - coming soon to a bookstore near you!

'I grew up on sets...The inner workings, the outer workings of being on a set is all I really know. I love that place,' Christina reflected; seen in 2022 in L.A.

And a few months earlier in May, Applegate gave a heartbreaking health update and revealed that she doesn't 'leave the house anymore'; seen in 2023 in L.A.